Physical Properties | | | |
Molecular Weight: 366.421 g/mol | logS: -3.75705 | SlogP: 1.97052 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0400709 | Sterimol/B1: 2.37605 | Sterimol/B2: 3.48566 | Sterimol/B3: 3.56556 |
Sterimol/B4: 7.86373 | Sterimol/L: 20.4303 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 674.524 | Positive charged surface: 411.926 | Negative charged surface: 262.599 | Volume: 356.5 |
Hydrophobic surface: 515.256 | Hydrophilic surface: 159.268 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |