Physical Properties | | | |
Molecular Weight: 381.455 g/mol | logS: -2.82335 | SlogP: 4.3849 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.252445 | Sterimol/B1: 2.22199 | Sterimol/B2: 4.23567 | Sterimol/B3: 4.94378 |
Sterimol/B4: 10.7352 | Sterimol/L: 13.6616 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 642.08 | Positive charged surface: 446.498 | Negative charged surface: 195.582 | Volume: 373 |
Hydrophobic surface: 532.188 | Hydrophilic surface: 109.892 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |