Physical Properties | | | |
Molecular Weight: 404.368 g/mol | logS: -4.93997 | SlogP: 3.3374 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.111551 | Sterimol/B1: 2.58333 | Sterimol/B2: 5.09482 | Sterimol/B3: 5.77999 |
Sterimol/B4: 8.54545 | Sterimol/L: 15.8385 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 634.87 | Positive charged surface: 310.547 | Negative charged surface: 324.324 | Volume: 349.75 |
Hydrophobic surface: 348.486 | Hydrophilic surface: 286.384 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 2 | Acid groups: 2 | Basic groups: 0 |
Chiral centers: 0 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |