Physical Properties | | | |
Molecular Weight: 418.324 g/mol | logS: -5.13704 | SlogP: 5.4419 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.131208 | Sterimol/B1: 2.17392 | Sterimol/B2: 5.13307 | Sterimol/B3: 5.53218 |
Sterimol/B4: 8.67979 | Sterimol/L: 17.9212 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 660.104 | Positive charged surface: 374.772 | Negative charged surface: 285.333 | Volume: 381.875 |
Hydrophobic surface: 579.199 | Hydrophilic surface: 80.905 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |