Physical Properties | | | |
Molecular Weight: 413.474 g/mol | logS: -4.6962 | SlogP: 1.27992 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.132089 | Sterimol/B1: 2.72474 | Sterimol/B2: 3.23847 | Sterimol/B3: 5.9379 |
Sterimol/B4: 6.9551 | Sterimol/L: 17.7348 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 622.937 | Positive charged surface: 343.209 | Negative charged surface: 279.727 | Volume: 373.125 |
Hydrophobic surface: 506.718 | Hydrophilic surface: 116.219 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 3 | Acid groups: 2 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |