Physical Properties | | | |
Molecular Weight: 376.456 g/mol | logS: -4.76181 | SlogP: 4.5708 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.110078 | Sterimol/B1: 2.74575 | Sterimol/B2: 3.21729 | Sterimol/B3: 4.867 |
Sterimol/B4: 10.1299 | Sterimol/L: 16.1745 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 637.919 | Positive charged surface: 417.904 | Negative charged surface: 214.273 | Volume: 371.25 |
Hydrophobic surface: 532.385 | Hydrophilic surface: 105.534 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |