Physical Properties | | | |
Molecular Weight: 405.498 g/mol | logS: -4.26305 | SlogP: 4.49597 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.201949 | Sterimol/B1: 3.09264 | Sterimol/B2: 3.84893 | Sterimol/B3: 5.80545 |
Sterimol/B4: 7.58567 | Sterimol/L: 17.5398 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 660.561 | Positive charged surface: 451.038 | Negative charged surface: 209.523 | Volume: 404.625 |
Hydrophobic surface: 588.021 | Hydrophilic surface: 72.54 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |