Physical Properties | | | |
Molecular Weight: 408.526 g/mol | logS: -1.73687 | SlogP: 0.9589 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.046513 | Sterimol/B1: 2.77767 | Sterimol/B2: 4.19424 | Sterimol/B3: 5.00722 |
Sterimol/B4: 5.74052 | Sterimol/L: 22.3826 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 721.866 | Positive charged surface: 550.055 | Negative charged surface: 171.811 | Volume: 410.125 |
Hydrophobic surface: 605.952 | Hydrophilic surface: 115.914 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 1 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |