Physical Properties | | | |
Molecular Weight: 375.516 g/mol | logS: -6.546 | SlogP: 5.15878 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0503132 | Sterimol/B1: 2.40703 | Sterimol/B2: 3.28513 | Sterimol/B3: 4.7191 |
Sterimol/B4: 8.68592 | Sterimol/L: 18.3245 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 670.937 | Positive charged surface: 416.648 | Negative charged surface: 254.289 | Volume: 395.375 |
Hydrophobic surface: 587.853 | Hydrophilic surface: 83.084 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |