Physical Properties | | | |
Molecular Weight: 424.972 g/mol | logS: -5.2936 | SlogP: 6.4181 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.170077 | Sterimol/B1: 2.36643 | Sterimol/B2: 3.58351 | Sterimol/B3: 6.57769 |
Sterimol/B4: 7.9888 | Sterimol/L: 16.4232 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 635.642 | Positive charged surface: 397.645 | Negative charged surface: 237.998 | Volume: 410.875 |
Hydrophobic surface: 551.869 | Hydrophilic surface: 83.773 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |