Physical Properties | | | |
Molecular Weight: 408.885 g/mol | logS: -4.63659 | SlogP: 5.2797 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.165541 | Sterimol/B1: 2.44868 | Sterimol/B2: 4.4028 | Sterimol/B3: 6.27174 |
Sterimol/B4: 8.90667 | Sterimol/L: 16.7616 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 650.664 | Positive charged surface: 360.174 | Negative charged surface: 290.49 | Volume: 382.5 |
Hydrophobic surface: 515.778 | Hydrophilic surface: 134.886 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |