Physical Properties | | | |
Molecular Weight: 418.489 g/mol | logS: -4.79004 | SlogP: 3.4837 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.130445 | Sterimol/B1: 2.55919 | Sterimol/B2: 4.05398 | Sterimol/B3: 7.0696 |
Sterimol/B4: 7.97782 | Sterimol/L: 18.6636 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 677.508 | Positive charged surface: 452.758 | Negative charged surface: 224.75 | Volume: 379.625 |
Hydrophobic surface: 567.52 | Hydrophilic surface: 109.988 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |