Physical Properties | | | |
Molecular Weight: 412.47 g/mol | logS: -6.57928 | SlogP: 2.9793 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0111391 | Sterimol/B1: 2.23139 | Sterimol/B2: 2.44502 | Sterimol/B3: 3.79886 |
Sterimol/B4: 8.03375 | Sterimol/L: 23.5541 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 701.543 | Positive charged surface: 429.17 | Negative charged surface: 272.373 | Volume: 373.875 |
Hydrophobic surface: 535.272 | Hydrophilic surface: 166.271 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |