Physical Properties | | | |
Molecular Weight: 426.56 g/mol | logS: -8.02538 | SlogP: 6.0094 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0805613 | Sterimol/B1: 3.05427 | Sterimol/B2: 3.84934 | Sterimol/B3: 5.07438 |
Sterimol/B4: 6.80806 | Sterimol/L: 20.4393 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 702.5 | Positive charged surface: 509.5 | Negative charged surface: 180.454 | Volume: 423.125 |
Hydrophobic surface: 641.842 | Hydrophilic surface: 60.658 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |