Physical Properties | | | |
Molecular Weight: 415.541 g/mol | logS: -6.38242 | SlogP: 5.15319 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0783056 | Sterimol/B1: 2.40737 | Sterimol/B2: 5.92146 | Sterimol/B3: 6.05824 |
Sterimol/B4: 6.89814 | Sterimol/L: 20.1116 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 724.543 | Positive charged surface: 473.228 | Negative charged surface: 246.034 | Volume: 420.125 |
Hydrophobic surface: 638.534 | Hydrophilic surface: 86.009 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |