Physical Properties | | | |
Molecular Weight: 401.466 g/mol | logS: -4.7923 | SlogP: 3.55449 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0581205 | Sterimol/B1: 2.08159 | Sterimol/B2: 3.90082 | Sterimol/B3: 4.11362 |
Sterimol/B4: 9.42044 | Sterimol/L: 19.5697 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 703.735 | Positive charged surface: 449.243 | Negative charged surface: 254.492 | Volume: 389.375 |
Hydrophobic surface: 602.615 | Hydrophilic surface: 101.12 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |