Physical Properties | | | |
Molecular Weight: 428.641 g/mol | logS: -5.2382 | SlogP: 6.03892 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.104275 | Sterimol/B1: 3.36062 | Sterimol/B2: 4.71254 | Sterimol/B3: 5.60787 |
Sterimol/B4: 8.87771 | Sterimol/L: 17.4489 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 692.414 | Positive charged surface: 429.076 | Negative charged surface: 263.337 | Volume: 448.125 |
Hydrophobic surface: 575.843 | Hydrophilic surface: 116.571 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |