Physical Properties | | | |
Molecular Weight: 405.542 g/mol | logS: -4.62113 | SlogP: 4.57249 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.137383 | Sterimol/B1: 2.53849 | Sterimol/B2: 3.97259 | Sterimol/B3: 6.09876 |
Sterimol/B4: 10.1474 | Sterimol/L: 17.3231 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 725.513 | Positive charged surface: 450.496 | Negative charged surface: 270.369 | Volume: 422.875 |
Hydrophobic surface: 599.515 | Hydrophilic surface: 125.998 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |