Physical Properties | | | |
Molecular Weight: 381.495 g/mol | logS: -4.05373 | SlogP: 5.0804 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.183201 | Sterimol/B1: 2.42792 | Sterimol/B2: 2.81394 | Sterimol/B3: 5.78684 |
Sterimol/B4: 11.4739 | Sterimol/L: 16.1215 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 660.071 | Positive charged surface: 414.574 | Negative charged surface: 245.497 | Volume: 386.875 |
Hydrophobic surface: 580.481 | Hydrophilic surface: 79.59 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |