Physical Properties | | | |
Molecular Weight: 397.37 g/mol | logS: -5.27517 | SlogP: 5.01257 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.153724 | Sterimol/B1: 2.19989 | Sterimol/B2: 6.41485 | Sterimol/B3: 6.59157 |
Sterimol/B4: 6.89013 | Sterimol/L: 14.9063 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 624.389 | Positive charged surface: 323.516 | Negative charged surface: 300.874 | Volume: 359.75 |
Hydrophobic surface: 561.705 | Hydrophilic surface: 62.684 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |