Physical Properties | | | |
Molecular Weight: 416.565 g/mol | logS: -5.83603 | SlogP: 4.18087 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0526046 | Sterimol/B1: 3.54761 | Sterimol/B2: 3.84002 | Sterimol/B3: 4.63295 |
Sterimol/B4: 5.13997 | Sterimol/L: 21.7918 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 718.414 | Positive charged surface: 528.512 | Negative charged surface: 189.902 | Volume: 398.375 |
Hydrophobic surface: 642.337 | Hydrophilic surface: 76.077 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |