Physical Properties | | | |
Molecular Weight: 405.498 g/mol | logS: -7.61411 | SlogP: 5.1155 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0488369 | Sterimol/B1: 3.55011 | Sterimol/B2: 4.17552 | Sterimol/B3: 4.61804 |
Sterimol/B4: 6.38918 | Sterimol/L: 21.6303 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 708.221 | Positive charged surface: 464.108 | Negative charged surface: 244.113 | Volume: 398.5 |
Hydrophobic surface: 578.144 | Hydrophilic surface: 130.077 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |