Physical Properties | | | |
Molecular Weight: 421.541 g/mol | logS: -6.02613 | SlogP: 4.94764 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.0861271 | Sterimol/B1: 2.19832 | Sterimol/B2: 3.27393 | Sterimol/B3: 6.68353 |
Sterimol/B4: 6.92156 | Sterimol/L: 19.1456 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 704.254 | Positive charged surface: 482.448 | Negative charged surface: 221.806 | Volume: 430.5 |
Hydrophobic surface: 599.813 | Hydrophilic surface: 104.441 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |