Physical Properties | | | |
Molecular Weight: 423.585 g/mol | logS: -5.12054 | SlogP: 4.41169 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0815835 | Sterimol/B1: 3.43168 | Sterimol/B2: 4.35732 | Sterimol/B3: 4.71736 |
Sterimol/B4: 10.5032 | Sterimol/L: 18.0003 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 775.491 | Positive charged surface: 554.714 | Negative charged surface: 220.777 | Volume: 424.625 |
Hydrophobic surface: 652.176 | Hydrophilic surface: 123.315 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |