Physical Properties | | | |
Molecular Weight: 403.547 g/mol | logS: -2.99054 | SlogP: 0.9163 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.0489403 | Sterimol/B1: 2.54114 | Sterimol/B2: 2.76557 | Sterimol/B3: 4.25963 |
Sterimol/B4: 13.4801 | Sterimol/L: 16.5904 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 747.45 | Positive charged surface: 595.638 | Negative charged surface: 151.812 | Volume: 415.875 |
Hydrophobic surface: 589.617 | Hydrophilic surface: 157.833 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 1 |
Chiral centers: 0 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |