Physical Properties | | | |
Molecular Weight: 408.522 g/mol | logS: -3.69692 | SlogP: 3.3562 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.122585 | Sterimol/B1: 2.58098 | Sterimol/B2: 2.84456 | Sterimol/B3: 6.37013 |
Sterimol/B4: 9.97962 | Sterimol/L: 17.8588 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 722.421 | Positive charged surface: 546.432 | Negative charged surface: 175.99 | Volume: 416.125 |
Hydrophobic surface: 578.321 | Hydrophilic surface: 144.1 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 2 |
Chiral centers: 3 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |