Physical Properties | | | |
Molecular Weight: 402.498 g/mol | logS: -5.76093 | SlogP: 3.82977 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.045392 | Sterimol/B1: 1.969 | Sterimol/B2: 3.31857 | Sterimol/B3: 4.3666 |
Sterimol/B4: 11.1372 | Sterimol/L: 20.0213 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 715.888 | Positive charged surface: 467.916 | Negative charged surface: 242.565 | Volume: 401.75 |
Hydrophobic surface: 628.566 | Hydrophilic surface: 87.322 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |