Physical Properties | | | |
Molecular Weight: 406.461 g/mol | logS: -5.1827 | SlogP: 3.70521 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.111442 | Sterimol/B1: 2.24712 | Sterimol/B2: 4.17796 | Sterimol/B3: 5.59219 |
Sterimol/B4: 6.66132 | Sterimol/L: 17.7409 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 664.328 | Positive charged surface: 422.156 | Negative charged surface: 242.172 | Volume: 380.875 |
Hydrophobic surface: 567.328 | Hydrophilic surface: 97 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |