Physical Properties | | | |
Molecular Weight: 315.393 g/mol | logS: -3.96095 | SlogP: 3.4157 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0476135 | Sterimol/B1: 3.53459 | Sterimol/B2: 3.58753 | Sterimol/B3: 3.94077 |
Sterimol/B4: 4.85121 | Sterimol/L: 18.7154 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 574.455 | Positive charged surface: 329.898 | Negative charged surface: 244.557 | Volume: 294.875 |
Hydrophobic surface: 416.968 | Hydrophilic surface: 157.487 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |