Physical Properties | | | |
Molecular Weight: 533.967 g/mol | logS: -9.30314 | SlogP: 5.7976 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0727256 | Sterimol/B1: 4.02232 | Sterimol/B2: 4.50296 | Sterimol/B3: 6.15376 |
Sterimol/B4: 9.6615 | Sterimol/L: 18.7284 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 773.29 | Positive charged surface: 328.569 | Negative charged surface: 433.65 | Volume: 470.625 |
Hydrophobic surface: 659.45 | Hydrophilic surface: 113.84 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 3 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 0 | Violations of Lipinski's rule: 2 | Oprea's lead like rule: 0 | |