Physical Properties | | | |
Molecular Weight: 513.477 g/mol | logS: -7.14639 | SlogP: 3.793 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.101495 | Sterimol/B1: 2.90422 | Sterimol/B2: 4.61913 | Sterimol/B3: 6.0915 |
Sterimol/B4: 9.99654 | Sterimol/L: 19.3852 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 744.797 | Positive charged surface: 412.406 | Negative charged surface: 332.391 | Volume: 445.875 |
Hydrophobic surface: 584.581 | Hydrophilic surface: 160.216 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 3 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |