Physical Properties | | | |
Molecular Weight: 449.575 g/mol | logS: -6.13823 | SlogP: 4.29037 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0227583 | Sterimol/B1: 2.23557 | Sterimol/B2: 4.61999 | Sterimol/B3: 5.17233 |
Sterimol/B4: 5.66529 | Sterimol/L: 24.8284 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 767.794 | Positive charged surface: 470.961 | Negative charged surface: 296.833 | Volume: 427.875 |
Hydrophobic surface: 644.774 | Hydrophilic surface: 123.02 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |