Physical Properties | | | |
Molecular Weight: 473.016 g/mol | logS: -7.25233 | SlogP: 7.5939 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.115393 | Sterimol/B1: 2.4126 | Sterimol/B2: 2.55578 | Sterimol/B3: 7.2121 |
Sterimol/B4: 9.05633 | Sterimol/L: 21.868 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 752.97 | Positive charged surface: 455.469 | Negative charged surface: 297.501 | Volume: 460.75 |
Hydrophobic surface: 663.681 | Hydrophilic surface: 89.289 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |