Physical Properties | | | |
Molecular Weight: 507.63 g/mol | logS: -5.39512 | SlogP: 6.127 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.137246 | Sterimol/B1: 2.70812 | Sterimol/B2: 2.95801 | Sterimol/B3: 5.86346 |
Sterimol/B4: 13.4867 | Sterimol/L: 18.7775 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 799.841 | Positive charged surface: 515.09 | Negative charged surface: 284.751 | Volume: 501.875 |
Hydrophobic surface: 694.537 | Hydrophilic surface: 105.304 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 0 | Violations of Lipinski's rule: 2 | Oprea's lead like rule: 0 | |