Physical Properties | | | |
Molecular Weight: 460.836 g/mol | logS: -5.83119 | SlogP: 4.4407 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.313864 | Sterimol/B1: 2.48965 | Sterimol/B2: 2.61576 | Sterimol/B3: 7.51911 |
Sterimol/B4: 9.00225 | Sterimol/L: 14.7837 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 664.312 | Positive charged surface: 396.821 | Negative charged surface: 267.492 | Volume: 378.75 |
Hydrophobic surface: 515.717 | Hydrophilic surface: 148.595 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |