Physical Properties | | | |
Molecular Weight: 417.404 g/mol | logS: -4.71169 | SlogP: 3.5561 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.111077 | Sterimol/B1: 2.71972 | Sterimol/B2: 2.9565 | Sterimol/B3: 5.51946 |
Sterimol/B4: 7.65585 | Sterimol/L: 15.9923 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 604.355 | Positive charged surface: 314.442 | Negative charged surface: 289.913 | Volume: 341.5 |
Hydrophobic surface: 387.26 | Hydrophilic surface: 217.095 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |