Physical Properties | | | |
Molecular Weight: 444.399 g/mol | logS: -8.31347 | SlogP: 6.8799 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0794874 | Sterimol/B1: 3.59598 | Sterimol/B2: 4.78178 | Sterimol/B3: 5.19747 |
Sterimol/B4: 5.94275 | Sterimol/L: 21.1418 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 716.65 | Positive charged surface: 313.672 | Negative charged surface: 402.977 | Volume: 388.375 |
Hydrophobic surface: 553.383 | Hydrophilic surface: 163.267 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 0 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |