Physical Properties | | | |
Molecular Weight: 433.508 g/mol | logS: -5.59653 | SlogP: 4.2831 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0177247 | Sterimol/B1: 2.52505 | Sterimol/B2: 2.94515 | Sterimol/B3: 4.12261 |
Sterimol/B4: 6.57579 | Sterimol/L: 25.3615 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 753.593 | Positive charged surface: 482.589 | Negative charged surface: 271.004 | Volume: 419 |
Hydrophobic surface: 638.344 | Hydrophilic surface: 115.249 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |