Physical Properties | | | |
Molecular Weight: 415.449 g/mol | logS: -6.33372 | SlogP: 4.0971 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0586953 | Sterimol/B1: 2.39862 | Sterimol/B2: 2.9173 | Sterimol/B3: 4.77353 |
Sterimol/B4: 12.2696 | Sterimol/L: 15.3759 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 707.392 | Positive charged surface: 451.166 | Negative charged surface: 256.226 | Volume: 389.875 |
Hydrophobic surface: 604.8 | Hydrophilic surface: 102.592 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |