Physical Properties | | | |
Molecular Weight: 403.55 g/mol | logS: -4.05431 | SlogP: 2.99824 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0363116 | Sterimol/B1: 3.83995 | Sterimol/B2: 4.11891 | Sterimol/B3: 4.33829 |
Sterimol/B4: 6.57047 | Sterimol/L: 21.5608 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 745.093 | Positive charged surface: 512.554 | Negative charged surface: 232.54 | Volume: 421.5 |
Hydrophobic surface: 613.931 | Hydrophilic surface: 131.162 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 1 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |