Physical Properties | | | |
Molecular Weight: 387.414 g/mol | logS: -7.12324 | SlogP: 5.3753 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0977707 | Sterimol/B1: 2.06187 | Sterimol/B2: 3.71987 | Sterimol/B3: 4.54545 |
Sterimol/B4: 9.84606 | Sterimol/L: 18.917 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 665.619 | Positive charged surface: 339.981 | Negative charged surface: 325.639 | Volume: 364 |
Hydrophobic surface: 561.589 | Hydrophilic surface: 104.03 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |