Physical Properties | | | |
Molecular Weight: 414.505 g/mol | logS: -5.49171 | SlogP: 5.79382 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.064571 | Sterimol/B1: 2.34015 | Sterimol/B2: 3.38038 | Sterimol/B3: 4.40843 |
Sterimol/B4: 10.1007 | Sterimol/L: 20.1475 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 714.985 | Positive charged surface: 456.413 | Negative charged surface: 254.646 | Volume: 414.75 |
Hydrophobic surface: 605.826 | Hydrophilic surface: 109.159 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |