Physical Properties | | | |
Molecular Weight: 386.472 g/mol | logS: -3.80083 | SlogP: 2.2949 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.091672 | Sterimol/B1: 2.47095 | Sterimol/B2: 3.44446 | Sterimol/B3: 4.35891 |
Sterimol/B4: 9.33089 | Sterimol/L: 17.9323 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 658.518 | Positive charged surface: 367.884 | Negative charged surface: 290.634 | Volume: 358.75 |
Hydrophobic surface: 527.243 | Hydrophilic surface: 131.275 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |