Physical Properties | | | |
Molecular Weight: 417.574 g/mol | logS: -4.32367 | SlogP: 3.504 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0599996 | Sterimol/B1: 2.38047 | Sterimol/B2: 4.22912 | Sterimol/B3: 5.16005 |
Sterimol/B4: 9.09219 | Sterimol/L: 17.8694 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 723.396 | Positive charged surface: 481.563 | Negative charged surface: 237.18 | Volume: 414.125 |
Hydrophobic surface: 538.605 | Hydrophilic surface: 184.791 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |