Physical Properties | | | |
Molecular Weight: 386.472 g/mol | logS: -4.01314 | SlogP: 3.18357 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.144593 | Sterimol/B1: 2.33821 | Sterimol/B2: 5.72728 | Sterimol/B3: 5.98315 |
Sterimol/B4: 6.19749 | Sterimol/L: 15.386 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 628.357 | Positive charged surface: 395.028 | Negative charged surface: 233.329 | Volume: 357.875 |
Hydrophobic surface: 457.188 | Hydrophilic surface: 171.169 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |