Physical Properties | | | |
Molecular Weight: 378.476 g/mol | logS: -4.89109 | SlogP: 4.05126 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0799365 | Sterimol/B1: 2.75254 | Sterimol/B2: 3.48725 | Sterimol/B3: 5.80041 |
Sterimol/B4: 5.81476 | Sterimol/L: 19.5669 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 682.4 | Positive charged surface: 440.978 | Negative charged surface: 236.657 | Volume: 378.375 |
Hydrophobic surface: 601.187 | Hydrophilic surface: 81.213 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |