Physical Properties | | | |
Molecular Weight: 421.562 g/mol | logS: -3.82743 | SlogP: 2.256 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.249266 | Sterimol/B1: 2.40422 | Sterimol/B2: 4.74626 | Sterimol/B3: 6.65334 |
Sterimol/B4: 8.09321 | Sterimol/L: 14.2222 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 630.846 | Positive charged surface: 450.159 | Negative charged surface: 180.687 | Volume: 400.75 |
Hydrophobic surface: 480.884 | Hydrophilic surface: 149.962 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |