Physical Properties | | | |
Molecular Weight: 401.918 g/mol | logS: -6.65458 | SlogP: 5.6005 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.142073 | Sterimol/B1: 3.49462 | Sterimol/B2: 3.68019 | Sterimol/B3: 6.77939 |
Sterimol/B4: 8.00101 | Sterimol/L: 16.9526 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 655.346 | Positive charged surface: 387.767 | Negative charged surface: 267.578 | Volume: 371.25 |
Hydrophobic surface: 565.184 | Hydrophilic surface: 90.162 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |