Physical Properties | | | |
Molecular Weight: 402.429 g/mol | logS: -4.96173 | SlogP: 4.592 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0692851 | Sterimol/B1: 2.23488 | Sterimol/B2: 2.25722 | Sterimol/B3: 5.31918 |
Sterimol/B4: 11.0069 | Sterimol/L: 17.7804 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 661.194 | Positive charged surface: 388.367 | Negative charged surface: 272.827 | Volume: 371.125 |
Hydrophobic surface: 554.489 | Hydrophilic surface: 106.705 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |