Physical Properties | | | |
Molecular Weight: 403.89 g/mol | logS: -5.64528 | SlogP: 4.0472 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0194175 | Sterimol/B1: 2.48471 | Sterimol/B2: 2.58465 | Sterimol/B3: 3.79607 |
Sterimol/B4: 8.48602 | Sterimol/L: 19.3499 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 644.799 | Positive charged surface: 407.407 | Negative charged surface: 237.392 | Volume: 351.125 |
Hydrophobic surface: 557.529 | Hydrophilic surface: 87.27 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |